Package: SCORPION 1.3.2

Daniel Osorio

SCORPION: Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks

Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis.

Authors:Daniel Osorio [aut, cre], Marieke L. Kuijjer [aut]

SCORPION_1.3.2.tar.gz
SCORPION_1.3.2.zip(r-4.7)SCORPION_1.3.2.zip(r-4.6)SCORPION_1.3.2.zip(r-4.5)
SCORPION_1.3.2.tgz(r-4.6-any)SCORPION_1.3.2.tgz(r-4.5-any)
SCORPION_1.3.2.tar.gz(r-4.7-any)SCORPION_1.3.2.tar.gz(r-4.6-any)
SCORPION_1.3.2.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
SCORPION/json (API)

# Install 'SCORPION' in R:

install.packages('SCORPION', repos = c('https://kuijjerlab.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/kuijjerlab/scorpion/issues

Datasets:

scorpionTest - Example single-cell gene expression, motif, and ppi data

On CRAN:

cell-type-specific comparative-edge-analysis gene-regulatory-network population-comparison protein-protein-interaction single-cell transcription-factors transcriptomics

5.36 score 27 stars 21 scripts 610 downloads 4 exports 30 dependencies

Last updated from:2252b12735. Checks:7 WARNING, 2 OK. Indexed: yes.

Target	Result	Time
linux-devel-x86_64	WARNING	500
source / vignettes	OK	191
linux-release-x86_64	WARNING	482
macos-release-arm64	WARNING	883
macos-oldrel-arm64	WARNING	773
windows-devel	WARNING	881
windows-release	WARNING	869
windows-oldrel	WARNING	920
wasm-release	OK	129

Exports:regressEdges runSCORPION scorpion testEdges

Dependencies:cli codetools cpp11 digest dplyr furrr future generics globals glue igraph irlba lattice lifecycle listenv magrittr Matrix parallelly pbapply pillar pkgconfig purrr R6 RANN rlang tibble tidyselect utf8 vctrs withr

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
Regression analysis of edges across ordered conditions	regressEdges
Run SCORPION across cell groups and return combined networks	runSCORPION
Build gene regulatory networks from single-cell RNA-seq data using PANDA	scorpion
Example single-cell gene expression, motif, and ppi data	scorpionTest
Test edges from SCORPION networks	testEdges