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SCORPION - Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks
Constructs cell-type-specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor-target regulatory relationships. It also provides statistical methods for differential edge analysis.
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cell-type-specificcomparative-edge-analysisgene-regulatory-networkpopulation-comparisonprotein-protein-interactionsingle-celltranscription-factorstranscriptomics
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